Bolasterone is a close structural relative to methyl-testosterone, differing only by the addition of another methyl group at C-7.This would, of course, account for its chemical name, dimethyltestosterone. This added C-7 methyl group, however, makes the activity of this steroid so far removed from that of methyltestosterone that a comparison in any form is difficult to justify. For starters, the dual methyl groups give the steroid the ability to avoid SHBG to a tremendous extent – in the blood it exists largely in an unbound (active) state. You may remember that this is one of the same reasons mibolerone (Cheque Drops) is so potent, and effective in microgram (not milligram) doses.The C-7 methyl group also interferes with the ability of the steroid to interact with 5-alpha reductase, so despite being a testosterone derivative, bolasterone should not convert to its "dihydro" derivative in the body. This means that the steroid is technically much more anabolic than androgenic in nature. The only real similarity between the two is like methyltestosterone, bolasterone probably converts to estrogen in the body. This is evidenced by studies with 7-methyl-nandrolone, which have demonstrated that, at least in this case, the addition of C-7 methylation did not interfere with aromatization.
I cannot give you much information about finding the most appropriate dose to use, as I don't know anybody that has actually used this drug. With the potency of the anabolic/androgenic index data though, I suspect you would not need all that much to see a good effect. If I had to guess I would think that a dose in the range of 10-30 mg daily would probably outperform most oral steroids on the market. In terms of safety, it is difficult to think that this steroid will present any unique hazard to the user. Early clinical studies seemed to report very favorably on this compound, with no mention of specific dangers or toxicity. It is a C-17 alpha alkylated (methylated) oral anabolic steroid though, and as such needs to be respected for the stressful nature that all such compounds display toward the liver.
Bolasterone was discontinued worldwide long before I knew what anabolic steroids even were, and not too many people speaking about the subject today are going to be able to give you firsthand information about the drug.The few people who think they have used it are likely confusing it with a counterfeit steroid called Bolasterone (purportedly made in East Germany but actually made in a U.S. underground lab) that was circulating in the 1980's. This product was labeled to contain the real thing, but in fact turned out to be little more than an overpriced mixture of readily available and cheap injectable steroids. I do expect, however, that this ages old steroid will emerge again. The supply list from at least one Chinese steroid manufacturing company has started to include bolasterone as a bulk chemical. With the ever-growing underground steroid manufacturing business, fueled by the manufactures in China, it is only a matter of time before some enterprising individual sees the value in producing a bolasterone tablet for the black market. Perhaps it has even been done already, at least on a smaller scale. The United States Anti-Doping Agency has added bolasterone to its list of prohibited anabolic steroids, along with norbolethone, just this year (2003). This may suggest that the USADA believes bolasterone has already been used as an undetectable designer steroid.